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KMID : 0614620150650010052
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Korean Journal of Gastroenterology
2015 Volume.65 No. 1 p.52 ~ p.56
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A Case of Nodular Regenerative Hyperplasia of the Liver Combined with Toxic Hepatitis
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Jin Sun-Mi
Song Sang-Hee
Cho Yang-Hyun
Shin Dae-Kyu
Shin Sun-Young
Kim Gwang-Il
Park Ha-Na
Rim Kyu-Sung
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Abstract
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Nodular regenerative hyperplasia (NRH) is an uncommon liver condition characterized by diffuse transformation of the hepatic parenchyma into regenerative nodules without fibrosis. Portal vasculopathy caused by abnormal hepatic venous flow may induce hepatocyte hyperplasia, which forms regenerative nodules. Underlying diseases or certain drugs may also be the cause of NRH. This condition is often underdiagnosed as the patients remain asymptomatic until development of portal hypertension, and histopathologic confirmation by liver biopsy is the only way of making a definite diagnosis. The management mainly involves prevention and treatment of the complications of portal hypertension. The frequency of diagnosis of NRH has increased rapidly in recent years, however, only a few cases have been reported in Korea. Here, we report on a case of NRH of the liver combined with toxic hepatitis.
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KEYWORD
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Nodular regenerative hyperplasia, Drug-induced liver injury, Liver diseases
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